Biotech goes suburban
Space demand pushes more firms out of Cambridge corridor
Author: Bill Archembeault, Journal Staff Date: 10/26/01 Publication: Boston Business Journal

 

By Bill Archambeault
Journal Staff


Cambridge may be the region's biotechnology epicenter, but demand for biotech space is also making an impact in the suburbs, from Malden to Billerica.

In fact, Woburn-based Cummings Properties LLC is planning to redevelop four or five properties it owns in the Medford area as speculative biotech buildings.

The decision to develop speculative biotech properties reflects the faith that real estate experts have in the biotech industry. It's one of the few encouraging signs in a sagging market plagued by negative net absorption, declining rents, increasing vacancy rates and little optimism for the foreseeable future.

But there's a shortage of lab space available, said Robert Yacobian, leasing officer for Cummings Properties.
"We just don't have what we need," he said. "We've made the decision to do speculative lab buildouts in some of our flex buildings. We're identifying those buildings in our portfolio that would be appropriate for a lab fit-out."

Of the 8 million square feet Cummings owns in the northern suburban market, nearly 1 million square feet is leased to biotech companies, Yacobian said, and he's seen an increase of more than 50 percent in the last 30 months. In all, the company has leases with 71 biotech companies, he said, including ArQule Inc., CardioTech International, Collagenesis Inc., Inotek Corp. and Proteome Inc.

The suburbs benefited from the explosion of high-technology companies a few years ago as companies expanded rapidly and gobbled up land anywhere and everywhere east of Interstate 495. Now, with biotechnology looking like one of the safer bets in an uncertain economy, the real estate industry is anticipating strong demand from biotech firms.

But unlike the high-flying, high-tech boom, experts consider biotech less risky.

"It's not the next dot-com," Yacobian said. "It's a mature industry. It's had its ups and its downs."

Antigenics Inc., a New York City-based company that develops medicine to treat cancer, infectious disease and autoimmune diseases, doubled in size from 30,000 square feet to 60,000 square feet this month at Commerce Way in Woburn, Yacobian said. And there are others in need of space. Most tenants considering the suburbs are in search of blocks around 5,000 square feet, though there are requests for larger ones out there, too, he said.

"Right now, we have three lab companies we're working with that require 15,000 square feet and six others under 10,000 square feet," he said.

Daniel Guenther, senior vice president and director of research for NAI Hunneman Commercial Co. of Boston, said that while many of the high-profile companies will remain in Cambridge, there is strong demand in the suburbs as well.

"My impression is that there's pretty strong demand, especially by the larger pharmaceutical companies," he said. "They're more comfortable having independent corporate campuses."

But, he said, targeting companies with requirements in the 5,000-square-foot range is a wise move. Most of those firms, he said, would probably stay within the confines of Route 128.

`Clearly demand'
Biotech isn't a large enough industry that it can prop up the region's real estate market, but there is enough demand to warrant landlords' attention, Guenther said. While Cambridge has a glut of office space sitting empty, it's far too expensive to renovate it to accommodate 16-foot ceilings and improved ventilation systems necessary for lab space.

Rehabbing old single-story flex space, however, is less expensive, and it can be renovated to fit a company's needs.
Guenther said the biotech industry has accounted for roughly 1 million square feet of net absorption in the last three years.

Most of that absorption--anywhere from two-thirds to three-fourths--ended up in Cambridge, including Amgen's 285,000-square-foot Cambridge Research Center, Genetics Institute's 215,000-square-foot 200 Cambridgepark Drive and Lyme Properties' 300,000-square-foot building for Genzyme Corp. and 275,000-square-foot building for Vertex Pharmaceuticals Inc.
But Boston and suburban locations are attracting more interest.

"There's clearly demand for laboratory space in the northern market, and there's very little existing supply," said David Connolly of Boston-based CB Richard Ellis/Whittier Partners. "It is fair to say that some of these single-story flex buildings are appropriate for conversion to lab use."

Zoning pass
But as biotech firms look to the suburbs to meet their space needs, some towns are positioned better than others. Biotech firms are looking for locations where local zoning regulations encourage biotech use and where other firms are clustered.
"Communities that have already put out the welcome mat, biotech firms are focusing on them," Guenther said.
Christopher Maietta, vice president at Combined Properties Inc., a Malden-based property owner and developer, is following the city's efforts to revamp its zoning regulations to encourage biotech use.
"In the case of some communities, they don't really have an extensive R & D welcome mat of any kind. It was more of an ancillary use," he said.

That works against cities and towns trying to tap into the biotech market because they still have to compete with the drawing power of Cambridge. With Harvard University, the Massachusetts Institute of Technology and teaching hospitals next door in Boston, smaller towns have to do more to attract clusters of biotech firms.

The VC factor

Venture capitalist firms also play a role, Maietta said. Some insist that the companies they're backing be located in Cambridge.
Combined Properties had talked to one early-stage biotech firm that was seeking 40,000 to 50,000 square feet of space. The company had considered one of Combined Properties' sites, but ultimately passed, Maietta said.

"What determined that they wouldn't come to Malden was their funding sources felt it was important to be in an established location and be able to recruit the necessary people," he said. "The rationale was that unless you were in one of these no-brainer locations, the company might have trouble attracting and retaining people."

Maietta said there are concerns about landlords relying too heavily on one industry, especially when fitting out space is expensive and tailored to a specific company.

"Anytime you're banking on one horse, there's risk associated with it," Maietta said. "How deep is the vein to be tapped?"
Guenther said that while dependence on a single industry does increase exposure, the biotech industry will continue to play an important role in this region.

"It looks like a strong industry overall," he said.