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The Boston
Globe - January 25, 2011
Amgen
buying Woburn company
Banker
and Tradesman
The biotechnology
company Amgen Inc. is bolstering its late-stage drug pipeline by buying
the privately held cancer drug maker BioVex Group, of Woburn, Mass., in
a deal that could be worth as much as $1 billion.
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Buzz ShareThis BioVexs drug candidate, OncoVex, is based on a virus
that attacks cancer cells, destroying tumors and stimulating the immune
system to fight cancer throughout the body.
Amgens net income
rose 10 percent in the fourth quarter on better sales of anti-infection
drugs and reduced taxes, the Thousand Oaks, Calif., company said yesterday.
Amgen earned $1.02
billion, or $1.08 per share, in the quarter ended in December, up from
$931 million, or 92 cents per share. Excluding one-time costs, Amgen posted
a profit of $1.17 per share.
Revenue edged up 1
percent to $3.84 billion, from $3.81 billion.
Analysts expected
a profit of $1.10 per share and $3.81 billion in revenue, according to
FactSet.
Separately, Amgen
said it expects the acquisition of BioVex to close in the first quarter.
It agreed to pay $425 million at closing and another $575 million if BioVexs
products reach regulatory and sales milestones.
OncoVex is in late-stage
testing as a treatment for metastatic melanoma, the most aggressive type
of skin cancer, and squamous cell carcinomas of the head and neck. BioVex
is also running an early stage clinical trial of the genital herpes vaccine
ImmunoVex.
Sales of Amgens
drugs Neulasta and Neupogen, which are used to prevent infections in chemotherapy
patients, rose 3 percent to $1.24 billion. The increase came mostly from
higher prices.
Changes in inventories
by wholesalers also aided its revenue, and tax credits boosted Amgens
quarterly results.
Sales of Amgens
anemia drugs Aranesp and Epogen continued to slide, declining a combined
9 percent to $1.22 billion because of lower demand, primarily for Epogen.
Sales of the two drugs have dropped in recent years because of safety
warnings and tighter restrictions on their use. Amgen reported $28 million
in sales of its newest drug, denosumab.
The drug is approved
under the name Prolia as a treatment for osteoporosis in postmenopausal
women, and it is sold as Xgeva for the prevention of bone fractures in
patients with advanced cancer. Amgen said Prolia sales totaled $20 million
and Xgeva sales reached $8 million.
Investors hope new
products will reinvigorate Amgens sales and help make up for declining
Aranesp and Epogen revenue.
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